Used as a key intermediate in medicinal chemistry for the synthesis of strained bioisosteres, particularly in drug discovery programs targeting improved pharmacokinetic properties. The compound enables the incorporation of the bicyclo[1.1.1]pentane (BCP) motif, which serves as a rigid, three-dimensional substitute for flat aromatic rings or linear aliphatic groups. This enhances metabolic stability, solubility, and target selectivity in pharmaceutical candidates. The tert-butylcarbamate (Boc) group provides protection for the amine, allowing controlled deprotection and further functionalization in multi-step syntheses. The iodomethyl handle facilitates cross-coupling reactions, such as Suzuki or Negishi couplings, enabling rapid diversification of molecular structures. Widely applied in the development of CNS drugs, kinase inhibitors, and PET tracers due to its favorable physicochemical properties and ease of late-stage modification.