Used primarily in medicinal chemistry as a rigid scaffold to mimic phenyl or other aromatic groups in drug design. Its unique cube-like structure provides high symmetry and stability, enhancing metabolic resistance and improving pharmacokinetic properties. Employed in the development of CNS agents, enzyme inhibitors, and receptor agonists/antagonists where spatial orientation of functional groups is critical. Also explored in materials science for creating high-energy density compounds and advanced polymers due to its strained hydrocarbon framework.