Mesityl iodide is primarily used in organic synthesis as a versatile reagent. It is often employed in the preparation of complex organic molecules, particularly in the formation of carbon-carbon and carbon-heteroatom bonds. Its application is notable in the synthesis of pharmaceuticals, where it acts as an intermediate in the production of active pharmaceutical ingredients (APIs). Additionally, it is used in the development of agrochemicals, contributing to the creation of pesticides and herbicides. In research, mesityl iodide is utilized in the study of reaction mechanisms and in the development of new synthetic methodologies. Its role in cross-coupling reactions, such as the Heck and Suzuki reactions, is particularly significant, enabling the construction of diverse organic frameworks.