(3-((tert-Butoxycarbonyl)amino)-5-(trifluoromethyl)phenyl)boronic acid
95%
Reagent
Code: #131578
CAS Number
1207351-03-8
blur_circular Chemical Specifications
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Molecular Information
Weight
305.06 g/mol
Formula
C₁₂H₁₅BF₃NO₄
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Registry Numbers
MDL Number
MFCD16293725
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Storage & Handling
Density
1.31±0.1 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds in pharmaceutical research. Serves as a key intermediate in the development of trifluoromethyl-containing drug candidates due to its boronic acid functionality and protected amine group. The tert-butoxycarbonyl (Boc) protection allows for selective deprotection and further functionalization in multi-step syntheses. Commonly applied in the preparation of kinase inhibitors and other bioactive molecules where the trifluoromethyl aryl motif enhances metabolic stability and binding affinity. Suitable for solid-phase and solution-phase peptide-like assembly when incorporated into complex molecular architectures.
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