3,5-Bis(trifluoromethyl)benzyl alcohol
98%
Reagent
Code: #143391
Alias
3,5-bistrifluoromethylbenzyl alcohol
3,5-bis(trifluoromethyl)benzyl alcohol
CAS Number
32707-89-4
blur_circular Chemical Specifications
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Molecular Information
Weight
244.13 g/mol
Formula
(CF₃)₂C₆H₃CH₂OH
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Registry Numbers
EC Number
251-168-9
MDL Number
MFCD00009907
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Physical Properties
Melting Point
53-56 °C(lit.)
Boiling Point
40°C 0,5mm
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in antifungal agents like fluconazole and related triazole derivatives. Its trifluoromethyl groups enhance metabolic stability and lipophilicity, improving drug penetration across biological membranes. Also employed in agrochemicals for developing fungicides and pesticides due to the electron-withdrawing nature of trifluoromethyl groups, which increases bioavailability and environmental stability. Additionally, serves as a building block in organic synthesis for creating fluorinated analogs in medicinal chemistry research.
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