Omiganan is primarily used as an antimicrobial agent in topical formulations to reduce the presence of bacteria and fungi on the skin. It has been investigated for its ability to prevent and treat infections in conditions such as acne and catheter-related infections due to its broad-spectrum activity. Its mechanism involves disrupting microbial cell membranes, which makes it effective against both gram-positive and gram-negative bacteria, as well as certain fungi. Because of its low potential for inducing resistance, Omiganan is considered a promising agent in managing skin colonization by pathogens like Staphylococcus aureus, including methicillin-resistant strains (MRSA). It is also being explored for use in wound care products to prevent infection and support healing in chronic or surgical wounds.