Amodiaquine is primarily used as an antimalarial drug, effective in treating and preventing malaria caused by Plasmodium falciparum and other Plasmodium species. It is often administered in combination with other antimalarial agents, such as artesunate, to enhance its efficacy and reduce the risk of drug resistance. This combination therapy is widely recommended in regions where malaria is endemic, particularly in Africa. Additionally, amodiaquine is utilized in areas where chloroquine resistance has become prevalent, as it offers an alternative treatment option. Its use is also explored in research for potential antiviral and anti-inflammatory properties, though these applications are not yet mainstream. Proper dosage and adherence to treatment regimens are crucial to minimize side effects and ensure effective malaria management.