6',7'-Dihydroxybergamottin is a furanocoumarin compound primarily found in grapefruit and studied as a reagent in pharmacological research. It is renowned for its potent inhibition of the CYP3A4 enzyme, a key player in drug metabolism, which can alter the bioavailability of various medications and is central to understanding grapefruit-drug interactions. This makes it valuable for developing strategies to manage drug efficacy and safety. Additionally, it is investigated for its antioxidant properties to mitigate oxidative stress, potential anti-inflammatory and anti-cancer effects, and in photochemistry for exploring photosensitization and light-induced reactions in compounds.