Clinafloxacin is primarily used as a broad-spectrum antibiotic, effective against a wide range of bacterial infections. It is particularly valuable in treating severe infections caused by multidrug-resistant bacteria, including those in the respiratory tract, skin, and urinary tract. Its potent activity against both Gram-positive and Gram-negative bacteria makes it a critical option in hospital settings for combating infections that are unresponsive to other antibiotics. Additionally, clinafloxacin has been investigated for its potential use in treating infections in immunocompromised patients, such as those with cystic fibrosis or undergoing chemotherapy. Its ability to penetrate tissues and cells effectively enhances its utility in targeting hard-to-treat infections. However, due to concerns about side effects, its use is often reserved for cases where other treatments have failed.