Used to treat a variety of bacterial infections, including acne, urinary tract infections, respiratory infections, and certain sexually transmitted infections like chlamydia. It is effective against both gram-positive and gram-negative bacteria and is often prescribed when other antibiotics are not suitable. Minocycline can cross the blood-brain barrier, making it useful in treating infections of the central nervous system, such as meningitis. It has also been studied for its anti-inflammatory and neuroprotective properties, showing potential in conditions like rheumatoid arthritis and neurodegenerative diseases such as Parkinson's and Alzheimer's. In ophthalmology, it is used to manage ocular rosacea and other inflammatory eye conditions. Additionally, it is sometimes used off-label for reducing intracranial pressure in pseudotumor cerebri.