5-[2-(Trifluoromethoxy)phenyl]-2H-tetrazole

95%

Reagent Code: #242585
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CAS Number 1261268-92-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 230.15 g/mol
Formula C₈H₅F₃N₄O
badge Registry Numbers
MDL Number MFCD18375292
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the preparation of sartan-class antihypertensive drugs such as losartan and valsartan. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the AT1 receptor. It is also employed in medicinal chemistry for developing bioisosteres due to its metabolic stability and improved lipophilicity. Additionally, it finds use in agrochemical research for designing novel active ingredients with enhanced activity and environmental stability.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿4,081.00
inventory 25g
10-20 days ฿42,251.00
inventory 5g
10-20 days ฿12,870.00

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