[5-(2-chlorophenyl)-2H-tetrazol-2-yl]acetic acid

97%

Reagent Code: #197346
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CAS Number 5626-38-0

science Other reagents with same CAS 5626-38-0

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Weight 238.63 g/mol
Formula C₉H₇ClN₄O₂
inventory_2 Storage & Handling
Storage 2-8°C, avoiding light

description Product Description

Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as valsartan and losartan. Its tetrazole ring mimics the carboxylic acid group in peptides, enhancing binding to the angiotensin II receptor. Commonly employed in pharmaceutical research and development for designing potent and selective blockers of the renin-angiotensin system. Also utilized in medicinal chemistry for constructing bioisosteres to improve metabolic stability and oral bioavailability in drug candidates.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿36,710.00
inventory 100mg
10-20 days ฿17,260.00

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[5-(2-chlorophenyl)-2H-tetrazol-2-yl]acetic acid
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Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as valsartan and losartan. Its tetrazole ring mimics the carboxylic acid group in peptides, enhancing binding to the angiotensin II receptor. Commonly employed in pharmaceutical research and development for designing potent and selective blockers of the renin-angiotensin system. Also utilized in medicinal chemistry for constructing bioisosteres to

Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as valsartan and losartan. Its tetrazole ring mimics the carboxylic acid group in peptides, enhancing binding to the angiotensin II receptor. Commonly employed in pharmaceutical research and development for designing potent and selective blockers of the renin-angiotensin system. Also utilized in medicinal chemistry for constructing bioisosteres to improve metabolic stability and oral bioavailability in drug candidates.

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