4-(2H-Tetrazol-5-yl)benzene-1-sulfonyl chloride

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Reagent Code: #192282
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CAS Number 924964-20-5

science Other reagents with same CAS 924964-20-5

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Weight 244.66 g/mol
Formula C₇H₅ClN₄O₂S
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MDL Number MFCD18432765
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used primarily as a key intermediate in the synthesis of angiotensin II receptor antagonists, such as valsartan and other sartan-class antihypertensive drugs. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding to the angiotensin receptor. The sulfonyl chloride group allows for efficient coupling with various amines, enabling the construction of complex drug molecules. Commonly employed in pharmaceutical research and development for creating biologically active compounds with improved metabolic stability and potency.

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inventory 1g
10-20 days ฿33,000.00

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4-(2H-Tetrazol-5-yl)benzene-1-sulfonyl chloride
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Used primarily as a key intermediate in the synthesis of angiotensin II receptor antagonists, such as valsartan and other sartan-class antihypertensive drugs. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding to the angiotensin receptor. The sulfonyl chloride group allows for efficient coupling with various amines, enabling the construction of complex drug molecules. Commonly employed in pharmaceutical research and development for creating biologically active compounds with improved metabolic stability and potency.
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