4-(2H-Tetrazol-5-yl)benzene-1-sulfonyl chloride
97%
Reagent
Code: #192282
CAS Number
924964-20-5
science Other reagents with same CAS 924964-20-5
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Molecular Information
Weight
244.66 g/mol
Formula
C₇H₅ClN₄O₂S
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Registry Numbers
MDL Number
MFCD18432765
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Storage & Handling
Storage
2-8°C
description Product Description
Used primarily as a key intermediate in the synthesis of angiotensin II receptor antagonists, such as valsartan and other sartan-class antihypertensive drugs. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding to the angiotensin receptor. The sulfonyl chloride group allows for efficient coupling with various amines, enabling the construction of complex drug molecules. Commonly employed in pharmaceutical research and development for creating biologically active compounds with improved metabolic stability and potency.
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