(4-(1H-Tetrazol-5-yl)phenyl)methanol
95%
Reagent
Code: #191790
CAS Number
501126-02-9
blur_circular Chemical Specifications
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Molecular Information
Weight
176.18 g/mol
Formula
C₈H₈N₄O
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Registry Numbers
MDL Number
MFCD09909570
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Storage & Handling
Storage
2-8°C
description Product Description
Used in pharmaceutical synthesis as an intermediate for angiotensin II receptor antagonists, particularly in the production of sartan-class drugs like valsartan and losartan. The tetrazole group enhances binding affinity to the angiotensin receptor, improving drug efficacy. The hydroxymethyl group allows further functionalization, enabling chemical modifications to optimize pharmacokinetic properties. Also employed in research for developing new bioactive molecules due to the metabolic stability and polarity provided by the tetrazole ring.
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