5-[4-(Methylsulfonamido)phenyl]-2H-tetrazole

≥97%

Reagent Code: #172280
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CAS Number 1261268-83-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 239.25 g/mol
Formula C₈H₉N₅O₂S
badge Registry Numbers
MDL Number MFCD18375289
inventory_2 Storage & Handling
Storage Room temperature, dry

description Product Description

Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as candesartan and valsartan. Its tetrazole ring mimics the carboxylic acid group in angiotensin II, allowing it to effectively bind to the AT1 receptor. This compound contributes to the enhanced bioavailability and receptor affinity of the final drug product. It is also employed in medicinal chemistry research for developing new bioactive molecules due to the tetrazole moiety’s metabolic stability and ability to participate in hydrogen bonding.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿7,340.00
inventory 5g
10-20 days ฿18,620.00

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