Hexamethonium hydroxide solution is primarily used in research settings as a ganglionic blocking agent. It effectively inhibits the transmission of nerve impulses in autonomic ganglia, making it a valuable tool in studying the autonomic nervous system. Researchers utilize it to investigate the physiological and pharmacological effects of blocking sympathetic and parasympathetic pathways, particularly in cardiovascular and neurological studies. Additionally, it has been employed in experimental models to understand hypertension and to explore the mechanisms of blood pressure regulation. Its application is largely confined to laboratory studies rather than clinical use.