Phloridzin dihydrate is widely used in research related to diabetes and metabolic disorders due to its ability to inhibit glucose transport proteins, particularly SGLT1 and SGLT2. This property makes it a valuable tool for studying glucose absorption in the intestines and kidneys, helping to understand and develop treatments for hyperglycemia and diabetes. Additionally, it is utilized in studies exploring its antioxidant and anti-inflammatory effects, which have potential applications in managing oxidative stress-related diseases. In the field of plant biology, it serves as a model compound for investigating polyphenol metabolism and its role in plant defense mechanisms. Its use in pharmacological and biochemical research continues to expand as scientists explore its therapeutic potential in various health conditions.