(S)-(−)-Perillyl alcohol is widely used in the pharmaceutical industry due to its potential anticancer properties. It has been studied for its ability to induce apoptosis in cancer cells and inhibit tumor growth, particularly in breast, prostate, and pancreatic cancers. Additionally, it is being explored for its chemopreventive effects, helping to reduce the risk of cancer development.

In the field of dermatology, it is utilized in skincare products for its antioxidant and anti-inflammatory properties, which help protect the skin from damage caused by free radicals and reduce signs of aging.

Furthermore, (S)-(−)-Perillyl alcohol is used in the flavor and fragrance industry as a component in perfumes and food flavorings, providing a fresh, citrus-like aroma. Its natural origin makes it a desirable ingredient in eco-friendly and natural product formulations.

Research is also ongoing into its potential use as a neuroprotective agent, with studies suggesting it may help in treating neurodegenerative diseases such as Alzheimer's and Parkinson's.