4-(Trifluoromethoxy)benzyl bromide

>97.0%(GC)

Reagent Code: #240033
label
Alias 4-(trifluoromethoxy)benzyl bromide; 4-(trifluoromethoxy)benzyl bromide; p-trifluoromethoxybenzyl bromide
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CAS Number 50824-05-0

science Other reagents with same CAS 50824-05-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 255.03 g/mol
Formula C₈H₆BrF₃O
badge Registry Numbers
MDL Number MFCD00061238
thermostat Physical Properties
Melting Point 22-24°C
Boiling Point 82-84 °C10 mm Hg(lit.)
inventory_2 Storage & Handling
Density 1.594 g/mL at 25 °C(lit.)
Storage 2~8°C

description Product Description

Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of fluorinated compounds with enhanced metabolic stability and bioavailability. Its reactivity as a benzyl bromide allows for efficient alkylation of nucleophiles such as amines and thiols, making it valuable in constructing complex organic molecules. Commonly employed in the preparation of selective serotonin reuptake inhibitors (SSRIs) and other bioactive agents where the trifluoromethoxy group contributes to improved lipophilicity and binding affinity. Also utilized in the manufacture of certain herbicides and fungicides due to the electron-withdrawing nature of the trifluoromethoxy moiety, which can enhance environmental stability and target specificity.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿260.00
inventory 5g
10-20 days ฿420.00
inventory 25g
10-20 days ฿1,230.00
inventory 100g
10-20 days ฿4,290.00
inventory 500g
10-20 days ฿18,600.00

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4-(Trifluoromethoxy)benzyl bromide
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Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of fluorinated compounds with enhanced metabolic stability and bioavailability. Its reactivity as a benzyl bromide allows for efficient alkylation of nucleophiles such as amines and thiols, making it valuable in constructing complex organic molecules. Commonly employed in the preparation of selective serotonin reuptake inhibitors (SSRIs) and other bioactive agents where the trifluoromethoxy g

Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of fluorinated compounds with enhanced metabolic stability and bioavailability. Its reactivity as a benzyl bromide allows for efficient alkylation of nucleophiles such as amines and thiols, making it valuable in constructing complex organic molecules. Commonly employed in the preparation of selective serotonin reuptake inhibitors (SSRIs) and other bioactive agents where the trifluoromethoxy group contributes to improved lipophilicity and binding affinity. Also utilized in the manufacture of certain herbicides and fungicides due to the electron-withdrawing nature of the trifluoromethoxy moiety, which can enhance environmental stability and target specificity.

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