Used primarily in peptide synthesis as a protected N-methyl amino acid derivative, specifically an arginine analog, this compound enables selective coupling and chain elongation in solid-phase peptide synthesis. Its Fmoc group allows for mild base-labile deprotection of the N-terminus, making it compatible with a wide range of side-chain protecting groups. The sulfonylguanidine moiety, protected with a 2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl (Pbf) group, enhances stability, solubility, and promotes specific interactions in biological target studies, particularly in the development of enzyme inhibitors. The N-methylation contributes to peptide backbone flexibility and metabolic stability in pharmaceutical applications. It is also employed in the preparation of structured peptides for use in pharmaceutical research, including protease substrates and receptor ligands.