Used in pharmaceutical research as a rigid amino acid analog, particularly in the design of enzyme inhibitors and bioactive molecules. Its strained bicyclic structure provides high metabolic stability and improved binding selectivity, making it valuable in optimizing peptide-based drugs. Commonly employed to replace traditional amino acids or linkers in drug candidates, enhancing pharmacokinetic properties such as oral bioavailability and target residence time. Also explored in PET tracer development due to its favorable polarity and potential for functionalization.