Widely used in biochemical and pharmaceutical research as a key intermediate for synthesizing arginine-rich peptides. Commonly employed in the development of protease inhibitors, particularly for enzymes involved in blood coagulation and fibrinolysis. Frequently utilized in studies related to thrombin and trypsin-like serine proteases due to its strong binding affinity. Also applied in cell-penetrating peptide conjugates to enhance intracellular delivery of biomolecules. Its dual guanidinium groups enable strong ionic interactions with phosphate groups on cell surfaces, improving uptake efficiency. Used in assays requiring high-affinity ligands for protein binding studies. Stable under standard lab conditions, making it suitable for solid-phase peptide synthesis and high-throughput screening applications.