(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(tetrahydro-2H-pyran-4-yl)propanoic acid
98%
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Widely used in peptide synthesis, this compound serves as a protected amino acid building block, particularly in solid-phase peptide synthesis (SPPS). The Fmoc group provides temporary protection to the amine functionality, allowing selective reaction at the carboxylic acid site. Its tetrahydro-2H-pyran-4-yl side chain offers structural similarity to natural amino acids, making it suitable for designing peptides with modified backbone properties. It is especially valuable in the preparation of complex peptides and peptidomimetics for pharmaceutical research, where stereochemistry and side chain stability are critical. The compound’s compatibility with Fmoc deprotection conditions enables stepwise elongation of peptide chains under mild basic conditions, preserving sensitive functional groups.
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