(1R,3S,4S)-3-(BOC-AMINO)-4-HYDROXY-CYCLOHEXANECARBOXYLIC ACID ETHYL ESTER
95%
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description Product Description
Used as a key chiral intermediate in the synthesis of pharmaceuticals, particularly in the development of protease inhibitors and other biologically active compounds. Its protected amine and hydroxyl groups allow for selective reactions in multi-step organic syntheses. Commonly employed in the preparation of peptidomimetics due to its rigid cyclohexane backbone and defined stereochemistry, which help mimic peptide structures while enhancing metabolic stability. The BOC-protected amine facilitates easy deprotection under mild acidic conditions, enabling further coupling reactions in solid-phase or solution-phase peptide synthesis. Its ester functionality can be hydrolyzed to the corresponding carboxylic acid for use in amide bond formation. Widely utilized in medicinal chemistry for structure-activity relationship (SAR) studies.
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