(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-(tert-butoxycarbonyl)piperidin-4-yl)propanoic acid
98%
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description Product Description
Widely used in peptide synthesis, this compound serves as a protected amino acid derivative, particularly in solid-phase peptide synthesis (SPPS). Its main role is to introduce a piperidine-containing amino acid residue into a growing peptide chain with high stereochemical control. The Fmoc group allows for mild base-labile protection of the alpha-amine, enabling stepwise assembly of peptides while remaining compatible with a wide range of side-chain protecting groups. The tert-butoxycarbonyl (Boc) group on the piperidine nitrogen provides acid-labile protection, which can be selectively removed under mild acidic conditions without affecting other sensitive functionalities. This dual protection strategy makes it valuable for synthesizing complex peptides and peptidomimetics, especially those targeting biological receptors where conformational restraint is important. It is also employed in the preparation of drug candidates and bioactive molecules in medicinal chemistry research.
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