Used in solid-phase peptide synthesis, this compound enables the incorporation of alkyne-functionalized amino acids into peptides. The alkyne group allows for bioorthogonal reactions, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC), commonly known as click chemistry. This is particularly valuable in labeling peptides with fluorescent tags, biotin, or other functional probes for imaging, detection, or pull-down assays. The Fmoc protection group ensures compatibility with standard Fmoc-t-Bu strategy, allowing stepwise assembly of complex peptides on resin. Its main application lies in the development of peptide-based probes, conjugation strategies, and chemical biology research where site-specific modification is required.