Widely used in pharmaceutical synthesis, this compound serves as a key chiral building block in the development of protease inhibitors and other bioactive molecules. Its protected proline core with a fluorinated benzyl substituent allows for selective modifications in peptide-based drugs, enhancing metabolic stability and target binding affinity. The trans configuration and Boc protection enable high stereocontrol during coupling reactions, making it valuable in solid-phase and solution-phase peptide synthesis. It is particularly useful in the preparation of enzyme inhibitors where proline conformation influences biological activity.