Used in solid-phase peptide synthesis as a protected amino acid building block, particularly for incorporating fluorinated aromatic side chains into peptides. The Fmoc group allows for mild base deprotection, compatible with standard Fmoc/tBu strategies. The trifluorinated phenylalanine derivative enhances peptide stability, lipophilicity, and can influence conformation due to electron-withdrawing effects. Commonly applied in the development of bioactive peptides, enzyme inhibitors, and pharmaceuticals where metabolic resistance and binding affinity are important. Also useful in studying structure-activity relationships in peptide-based research.