Used in peptide synthesis as a protected amino acid building block, particularly in the production of therapeutic peptides and research compounds. The Fmoc group allows for solid-phase synthesis by enabling selective deprotection under mild basic conditions, while the D-configuration of the piperidine-2-carboxylic acid (Pip) moiety introduces structural rigidity and metabolic stability to the resulting peptide. Commonly employed in the development of peptidomimetics, enzyme inhibitors, and bioactive peptides where conformational control is critical. Its use supports the synthesis of foldamers and other structured peptides that require non-natural amino acids to achieve desired biological activity or stability.