trans-3-(Boc-aminomethyl)cyclobutylamine is used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of bioactive molecules and drug candidates. Its trans-cyclobutane core features a free primary amine and a Boc-protected aminomethyl group, enabling selective functionalization and making it valuable in medicinal chemistry for building complex amines. The conformational rigidity of the cyclobutane ring and its ability to mimic peptide bonds make it commonly employed in the preparation of protease inhibitors and receptor modulators. It is also utilized in the design of small molecule therapeutics targeting neurological and metabolic disorders.