N-methoxy-N-methyloctanamide
95%
blur_circular Chemical Specifications
description Product Description
N-Methoxy-N-methyloctanamide is a Weinreb amide, a specialized synthetic intermediate derived from octanoic acid. It is primarily used in organic synthesis to facilitate the controlled formation of ketones. Unlike simple esters, Weinreb amides react with one equivalent of organometallic reagents (e.g., Grignard or organolithium compounds) to produce ketones in high yield, preventing over-addition through intramolecular chelation involving the N-methoxy group. This makes it valuable for constructing complex molecules in medicinal chemistry, natural product synthesis, and materials science. The C8 alkyl chain provides lipophilicity, suitable for applications involving longer-chain derivatives. It is stable under standard handling conditions and compatible with various reaction setups.
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