Propargyl-PEG5-OH is widely used in bioconjugation and chemical synthesis due to its unique properties. It serves as a linker molecule in the development of drug delivery systems, enabling the attachment of therapeutic agents to targeting molecules or nanoparticles. This enhances the specificity and efficiency of drug delivery. Additionally, it is employed in the synthesis of polymers and hydrogels, where its terminal hydroxyl group allows for further functionalization. In material science, it is utilized to modify surfaces or create functionalized materials for applications like biosensors and coatings. Its propargyl group also makes it valuable in click chemistry reactions, facilitating the rapid and efficient assembly of complex molecules.