Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of biologically active compounds where the trifluoromethyl group enhances metabolic stability and lipophilicity. Its rigid cyclobutane scaffold with defined stereochemistry makes it valuable in medicinal chemistry for optimizing potency and selectivity in drug candidates. Commonly employed in the design of enzyme inhibitors and receptor modulators, especially in central nervous system agents and anti-inflammatory drugs. Also utilized in agrochemicals to improve the environmental stability and efficacy of active ingredients.