4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid
98%
Reagent
Code: #149694
CAS Number
16506-27-7
blur_circular Chemical Specifications
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Molecular Information
Weight
358.26 g/mol
Formula
C₁₆H₂₁Cl₂N₃O₂
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Registry Numbers
MDL Number
MFCD00866481
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Physical Properties
Boiling Point
585.16 °C at 760 mmHg (lit.)
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Storage & Handling
Density
1.31 g/cm3 at 25 °C (lit.)
Storage
2-8°C, dry
description Product Description
Used as an intermediate in the synthesis of targeted cancer therapies, particularly in the development of antibody-drug conjugates (ADCs). Its structure allows for selective alkylation of DNA, making it valuable in creating cytotoxic agents that can be directed specifically to tumor cells. The carboxylic acid group enables conjugation to monoclonal antibodies via linker systems, facilitating controlled drug delivery. This compound is especially explored in treatments for hematological malignancies due to its potent mechanism of action and modifiable release profile.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | solid |
| Purity (%) | 97.5-100% |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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