N-(14-Amino-3,6,9,12-tetraoxatetradecyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride

95%

Reagent Code: #109002
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CAS Number 2245697-85-0

science Other reagents with same CAS 2245697-85-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 587.02 g/mol
Formula C₂₅H₃₅ClN₄O₁₀
badge Registry Numbers
MDL Number MFCD31656718
inventory_2 Storage & Handling
Storage -20°C, store under inert gas

description Product Description

This compound is primarily utilized in the field of targeted drug delivery, particularly in the development of antibody-drug conjugates (ADCs). It serves as a linker-payload system, where the molecule connects a cytotoxic agent to a monoclonal antibody, enabling precise delivery of the drug to cancer cells. The chemical structure includes a polyethylene glycol (PEG) spacer, which enhances solubility and stability, and a cleavable linker that releases the active drug payload upon reaching the target site. Its application is significant in oncology, as it helps minimize off-target effects and improve therapeutic efficacy. Additionally, the compound is used in proteolysis-targeting chimeras (PROTACs) for targeted protein degradation, offering potential in treating diseases caused by aberrant protein expression.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿28,611.00
inventory 250mg
10-20 days ฿42,912.00

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N-(14-Amino-3,6,9,12-tetraoxatetradecyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride
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This compound is primarily utilized in the field of targeted drug delivery, particularly in the development of antibody-drug conjugates (ADCs). It serves as a linker-payload system, where the molecule connects a cytotoxic agent to a monoclonal antibody, enabling precise delivery of the drug to cancer cells. The chemical structure includes a polyethylene glycol (PEG) spacer, which enhances solubility and stability, and a cleavable linker that releases the active drug payload upon reaching the target site.

This compound is primarily utilized in the field of targeted drug delivery, particularly in the development of antibody-drug conjugates (ADCs). It serves as a linker-payload system, where the molecule connects a cytotoxic agent to a monoclonal antibody, enabling precise delivery of the drug to cancer cells. The chemical structure includes a polyethylene glycol (PEG) spacer, which enhances solubility and stability, and a cleavable linker that releases the active drug payload upon reaching the target site. Its application is significant in oncology, as it helps minimize off-target effects and improve therapeutic efficacy. Additionally, the compound is used in proteolysis-targeting chimeras (PROTACs) for targeted protein degradation, offering potential in treating diseases caused by aberrant protein expression.

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