PEG-TE-LiAc solution is widely used in molecular biology for the transformation of yeast cells. It facilitates the introduction of foreign DNA into yeast, making it essential for genetic engineering and cloning experiments. The solution works by making the yeast cell walls more permeable, allowing DNA to enter the cells efficiently. It is particularly useful in creating recombinant yeast strains for research in biotechnology, pharmaceuticals, and industrial applications. Additionally, it is employed in studies involving gene function, protein expression, and metabolic pathway engineering in yeast systems.