SJB2-043 is primarily utilized in research settings, particularly in the study of cancer biology. It functions as a potent and selective inhibitor of the tankyrase enzyme, which plays a critical role in the Wnt/β-catenin signaling pathway. This pathway is often dysregulated in various cancers, making SJB2-043 a valuable tool for investigating potential therapeutic strategies. Researchers use it to explore its effects on tumor growth and metastasis, aiming to develop targeted cancer treatments. Additionally, it aids in understanding the molecular mechanisms underlying cellular processes such as DNA repair and telomere maintenance. Its application extends to preclinical studies where its efficacy and safety are evaluated in model systems.