SKL2001 is a small molecule modulator of the Wnt/β-catenin signaling pathway, primarily used in research settings to study cellular processes such as differentiation, proliferation, and tissue regeneration. It acts as an activator of the pathway by stabilizing β-catenin through inhibition of its degradation, making it a valuable tool in stem cell research and regenerative medicine studies. It has been investigated for its potential to promote osteogenic differentiation, suggesting possible applications in bone repair and treatment of degenerative bone diseases. Additionally, SKL2001 is used to explore the role of Wnt signaling in cancer development, offering insights into novel therapeutic strategies. Due to its role in enhancing tissue regeneration, it is also studied in neurodegenerative disease models and wound healing research.