Mouse DKK2, Tag Free is primarily used in biochemical and cellular research focused on the Wnt signaling pathway. It serves as a critical tool for studying the regulation of Wnt-mediated processes such as embryonic development, cell differentiation, and tissue homeostasis. Researchers use this protein to investigate its role as an antagonist of Wnt signaling by binding to LRP5/6 co-receptors, thereby modulating pathway activity. It is commonly applied in cell-based assays and protein interaction studies to explore molecular mechanisms in development and disease models, particularly in cancer and bone metabolism. Due to its tag-free nature, it allows for more accurate assessment of native protein interactions and signaling effects without interference from affinity tags. This makes it valuable in structural studies and functional assays requiring high biological fidelity.