Used in research to study Wnt signaling pathways, particularly in development and disease. Helps in understanding cellular processes like differentiation and proliferation. Applied in assays to investigate interactions with Wnt ligands and receptors. Valuable in cancer research due to the role of SFRP3 in tumor suppression. Also utilized in regenerative medicine studies, especially in cartilage and joint health. Supports development of therapeutics targeting Wnt-related conditions.