SKL2001 is primarily used in biomedical research due to its ability to modulate the Wnt/β-catenin signaling pathway. This pathway plays a crucial role in cell proliferation, differentiation, and tissue homeostasis, making SKL2001 valuable in studying diseases like cancer, where Wnt signaling is often dysregulated. Researchers utilize it to activate β-catenin signaling, enabling the investigation of its effects on tumor growth, stem cell maintenance, and tissue regeneration. Additionally, SKL2001 is employed in drug discovery to identify potential therapeutic targets for cancers and other conditions linked to abnormal Wnt signaling. Its application extends to studying bone formation and repair, as Wnt signaling is essential for skeletal development.