(tert-Butoxycarbonylmethyl)triphenylphosphonium chloride

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Reagent Code: #76736
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CAS Number 35000-37-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 412.89 g/mol
Formula C₂₄H₂₆ClO₂P
badge Registry Numbers
MDL Number MFCD00043160
thermostat Physical Properties
Melting Point 191-193°C
inventory_2 Storage & Handling
Storage 2-8°C, stored in argon

description Product Description

This compound is a specialized phosphonium salt used primarily as a Wittig reagent precursor in organic synthesis. Upon deprotonation, it forms the ylide (tert-butoxycarbonylmethylene)triphenylphosphorane, which reacts with aldehydes or ketones to produce α,β-unsaturated tert-butyl esters. These intermediates are crucial for constructing carbon-carbon double bonds in the synthesis of pharmaceuticals, agrochemicals, and bioactive molecules. The tert-butoxycarbonyl (Boc) group serves as a protecting moiety for the ester, which can be selectively deprotected under acidic conditions to afford the corresponding α,β-unsaturated carboxylic acids. This makes it a valuable tool in medicinal chemistry for building complex molecular frameworks with precise control over functional group reactivity.

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Size Availability Unit Price Quantity
inventory 5g
10-20 days ฿1,431.00
inventory 25g
10-20 days ฿4,320.00
inventory 100g
10-20 days ฿15,219.00

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