This mixture of anions—fluoride, chloride, nitrate, and sulfate—is commonly encountered in environmental and industrial water systems. It is particularly relevant in wastewater analysis, where the simultaneous presence of these ions indicates contamination from agricultural runoff, industrial discharges, or municipal sources. Fluoride and chloride are often monitored in drinking water to ensure safety and compliance with regulatory standards. Nitrate is a key indicator of nutrient pollution, especially from fertilizers or sewage, and its detection is critical in preventing health risks like methemoglobinemia. Sulfate contributes to water corrosivity and can affect the taste and odor of drinking water. In industrial processes, such as semiconductor manufacturing or metal treatment, monitoring this anion combination helps control etching, cleaning, and plating efficiency. Ion chromatography is typically used to analyze these anions in complex matrices. The combined profile aids in source tracking, process optimization, and environmental compliance across sectors including water treatment, mining, and chemical production.