This mixture of anions—fluoride, chloride, nitrate, and sulfate—is commonly encountered in environmental and industrial water systems. It is particularly relevant in water quality analysis, where the presence and concentration of these ions indicate contamination sources, corrosion potential, or treatment efficiency. Fluoride and chloride are often monitored in drinking water to ensure compliance with health standards, as excessive fluoride can cause dental or skeletal fluorosis, while chloride contributes to water salinity and infrastructure corrosion. Nitrate levels are critical in agricultural runoff assessments, as high concentrations pose risks to human health and aquatic ecosystems. Sulfate is evaluated for its role in acid mine drainage and its impact on concrete degradation in construction materials. The combined analysis of these anions is essential in wastewater treatment, boiler water control, and soil leachate studies, helping to design effective purification processes and environmental protection strategies.