Used in environmental and forensic laboratories for the calibration and validation of analytical instruments detecting chloral hydrate and its metabolites. Commonly applied in water quality testing to measure disinfection byproducts in drinking water, especially after chlorine treatment. Also utilized in clinical toxicology to quantify chloral hydrate levels in biological samples, supporting diagnosis and monitoring of exposure or overdose. Ensures accuracy and reliability in analytical methods such as gas chromatography and mass spectrometry.