Used primarily to treat symptoms of benign prostatic hyperplasia (BPH), silodosin helps improve urine flow by relaxing the muscles in the prostate and bladder neck. It selectively targets alpha-1A adrenergic receptors, which are involved in prostate smooth muscle contraction. This action reduces urinary hesitancy, urgency, weak stream, and frequent nighttime urination. Due to its high selectivity, it has a lower impact on blood pressure compared to other alpha-blockers, making it suitable for patients concerned about cardiovascular side effects.