3-(2,3,4,5-Tetrafluorophenyl)prop-2-enoic acid
Reagent
Code: #239008
CAS Number
16582-95-9
blur_circular Chemical Specifications
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Molecular Information
Weight
220.12 g/mol
Formula
C₉H₄F₄O₂
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated active pharmaceutical ingredients (APIs) where the tetrafluorophenyl group enhances metabolic stability and bioavailability. Its α,β-unsaturated carboxylic acid structure allows for conjugation reactions, making it valuable in medicinal chemistry for building blocks in anti-inflammatory and anticancer agents. Also employed in agrochemical research for designing novel pesticides with improved environmental resistance. The compound’s fluorine substitution pattern influences lipophilicity and binding affinity, which is exploited in structure-activity relationship (SAR) studies.
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