3-(2,3,4,5-Tetrafluorophenyl)prop-2-enoic acid
science Other reagents with same CAS 16582-95-9
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Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated active pharmaceutical ingredients (APIs) where the tetrafluorophenyl group enhances metabolic stability and bioavailability. Its α,β-unsaturated carboxylic acid structure allows for conjugation reactions, making it valuable in medicinal chemistry for building blocks in anti-inflammatory and anticancer agents. Also employed in agrochemical research for designing novel pesticides with improved environmental resistance. The compound’s fluorine substitution pattern influences lipophilicity and binding affinity, which is exploited in structure-activity relationship (SAR) studies.
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