(E)-Methyl 4,4,4-trifluorobut-2-enoate
98%
Reagent
Code: #186258
CAS Number
85694-31-1
science Other reagents with same CAS 85694-31-1
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Molecular Information
Weight
154.09 g/mol
Formula
C₅H₅F₃O₂
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Registry Numbers
MDL Number
MFCD26794215
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Storage & Handling
Storage
2-8°C, sealed, dry, light-proof
description Product Description
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals due to the presence of the trifluoromethyl group, which enhances metabolic stability and bioavailability. Its α,β-unsaturated ester structure allows for Michael addition reactions, making it valuable in constructing complex organic molecules. Commonly employed in medicinal chemistry for building blocks in drug discovery, particularly in the development of fluorinated analogs with improved pharmacokinetic properties. Also utilized in the preparation of specialty polymers and functional materials where fluorine imparts unique thermal and chemical resistance.
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