(E)-tert-Butyl3-cyclopropylacrylate
97%
Reagent
Code: #186140
CAS Number
1643971-46-3
blur_circular Chemical Specifications
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Molecular Information
Weight
168.23 g/mol
Formula
C₁₀H₁₆O₂
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Storage & Handling
Storage
Room temperature
description Product Description
Used in organic synthesis as a versatile building block for pharmaceuticals and agrochemicals. The α,β-unsaturated ester structure allows it to participate in Michael additions and cycloaddition reactions, facilitating the construction of complex cyclic and functionalized molecules. Its tert-butyl ester group offers stability under various reaction conditions and can be easily deprotected to yield carboxylic acid intermediates. The cyclopropyl moiety contributes conformational rigidity, making it valuable in medicinal chemistry for modulating bioavailability and metabolic stability in drug candidates. Commonly employed in the development of active pharmaceutical ingredients (APIs) where structural constraint enhances target selectivity.
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