(E)-4,4,4-Trifluorobut-2-enoic acid
97%
Reagent
Code: #185277
CAS Number
406-94-0
blur_circular Chemical Specifications
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Molecular Information
Weight
140.06 g/mol
Formula
C₄H₃F₃O₂
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Registry Numbers
MDL Number
MFCD02181180
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Storage & Handling
Storage
2-8°C, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated compounds with enhanced metabolic stability and bioavailability. Its α,β-unsaturated carbonyl structure with trifluoromethyl group allows for Michael addition reactions and conjugate additions, making it valuable in medicinal chemistry for building fluorinated scaffolds. Commonly employed in the preparation of enzyme inhibitors and bioactive molecules where fluorine substitution improves binding affinity and resistance to oxidative degradation. Also utilized in agrochemical research for designing novel pesticides and herbicides with improved environmental stability and potency.
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